The number of blockages in the capital's sewers has risen to five every hour, a 30 percent increase on last year.
That's according to a new report from City Hall, which says Thames Water is removing 30 tonnes of unflushable material from its sites, every day.
The London Assembly says many people are still unaware that items like wet wipes, and sanitary products wont break down because they contain plastic, and combined with fat and oil, are creating giant fatbergs.
Sewage blockages cost Thames Water and ultimately consumers £12 million a year, and the majority has to be sent for incineration, adding to London's carbon emissions and polluting the air.
in our rivers and oceans, sit in landfills or are incinerated, inflicting irreparable damage on our environment.
"We urgently need to educate Londoners not to flush these items down the toilet and enlist the help of the Mayor to take some practical steps to help the situation.
"London has to learn to bin it and not flush it."
Stephen Pattenden, Waste Network Performance Manager, Thames Water said:
"Many people don't realise how wipes that get flushed can cause blockages and fatbergs in the sewers. They contain plastic so don't break down in the same way as toilet paper does, instead clinging to the insides of the pipes and combining with fat and grease to form the fatbergs, which have become so common across London.
"It's great to have the London Assembly's help to spread our 'bin it' message across the capital."